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From seizure disorders to substance abuse to anxiety and depression, a growing body of research supports CBD as a safe, non-habit-forming alternative for a wide range of conditions and ailments. Learn more about the latest scientific research below.

More and more studies are extending the list of cannabidiol’s health and wellness benefits

The recent proliferation of cannabidiol (CBD) products on the market and the loosening of federal and local regulations governing the industry have led to what The New York Times Magazine called a “vernacular” movement that’s lending positivity and excitement to CBD’s growing presence. But what does science have to say about the safe and effective use of CBD products?

A wealth of research has shown that CBD interacts with the endocannabinoid system, a collection of cell receptors and molecules in the human body that helps regulate essential functions such as sleep, appetite, mood, and pain. And a growing body of research supports CBD’s potential benefits for a wide range of conditions and ailments.

At Crescent Canna, we’re actively following the science to keep our customers informed about the latest research and developments. Here are just a few of the most recent scientific developments involving the use of CBD:

Seizure Disorders

The United States Food and Drug Administration (FDA) has officially called CBD beneficial for people with neurological and seizure disorders. Importantly, in 2018, the FDA approved the use of Epidiolex, a prescription drug with CBD as its active ingredient. Epidiolex can be used to reduce seizures in two rare forms of epilepsy (Dravet Syndrome and Lennox-Gastaut Syndrome).

One study published this year looked at quality of life (QOL) in adults enrolled in an open-label study of CBD for treatment-resistant epilepsy. The study found that QOL had “significantly improved after one year of CBD treatment,” and also noted, “CBD may have independent positive effects on QOL beyond improved seizure control.”

Another 2019 study, published in the Journal of the American Veterinary Medical Association, assessed the effect of orally administered CBD on seizure frequency in dogs with epilepsy. Like humans, dogs (and cats and horses) have an endocannabinoid system. CBD was used along with conventional antiepileptic treatment. Results showed that the dogs in the CBD group “had a significant […] reduction in seizure frequency, compared with the placebo group.” And, not surprisingly, the dogs’ owners reported no adverse behavioral effects.

Substance Use and Addiction Treatment

Early animal and human studies delivered some promising findings indicating that CBD might be useful in treating opioid addiction and other forms of substance abuse. There’s also evidence from some pilot studies that suggests CBD may help users reduce cravings and symptoms associated with substance-use disorders (e.g., insomnia, anxiety, pain, drastic mood changes, etc.)

The latest animal study discovered unique anti-relapse potential of CBD when it looked at the possibilities of CBD treatment of substance use disorders. It looked at several classes of addiction — THC, nicotine, opiates, and alcohol — at various stages of addiction, including withdrawal. One major positive discovery was that “CBD attenuates cue-induced heroin reinstatement with effects that outlasted treatment by two weeks.”

The study cited CBD’s anti-anxiety and anti-craving effects among therapeutic benefits, noting:

CBD may be suitable for targeting several relapse-promoting factors: craving associated with drug cue exposure, susceptibility to stress, heightened anxiety, and impaired impulse control.

Anxiety and Depression Relief

Preliminary research has shown that CBD may change the way the brain’s receptors respond to serotonin, thus delivering some relief linked to mental health.

An important case series published last January in The Permanente Journal looked at CBD’s effect on anxiety and sleep, concluding that “evidence points toward a calming effect for CBD in the central nervous system.” It also cited an anti-anxiety effect in particular, along with better tolerance of CBD than routine psychiatric medications.

The latest animal study that looked at CBD’s effect on anxiety noted a reduction in anxiety-related behavior in mice. Another animal study published in the July 2019 issue of Journal of Chemical Neuroanatomy demonstrates a rapid and sustained antidepressant effect of CBD.

This is just a small sample of recent scientific research around the potential benefits of CBD, and just about every month we’re seeing new research emerge extending the list of CBD’s applications and benefits.

Stay tuned to the Crescent Canna blog for the latest news, trends, and research on this amazing compound.



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