THC, CBD, and the Endocannabinoid System

Cannabinoids bring balance to the body by interacting with the endocannabinoid system.

By interacting with the body’s endocannabinoid system, cannabinoids like THC and CBD beneficially affect various crucial functions.

One of the most important systems in your body is the endocannabinoid system (ECS), which regulates dozens of crucial functions along with being integral to maintaining homeostasis.

It would surprise many people to know we owe the discovery of this system to cannabis.

We were unaware of the endocannabinoid system and its impact until researchers in the 1990s discovered it through studying the effects of cannabis. Since then, we’ve learned a lot more about the system and how different cannabinoids affect it.


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What Is the Endocannabinoid System?

The endocannabinoid system consists of endocannabinoids, endocannabinoid receptors, and enzymes that break down endocannabinoids.

Endocannabinoids are cannabinoids that are naturally produced in your body. Since they are produced as needed, endocannabinoid levels tend to fluctuate.

By binding to receptors throughout your body, endocannabinoids signal your body to take action. The endocannabinoid system regulates various organs and tissues in your body, along with important functions like appetite and memory.

The two main types of endocannabinoids receptors are CB1 and CB2. CB1 receptors are mostly found in the central nervous system. They affect brain activity, immunity, appetite, and perception of pain. CB2 receptors are mostly found in the peripheral nervous system. They affect skin, organs, tissues, and muscles.

What Are Cannabinoids?

Cannabinoids interact with the endocannabinoids system in almost the same way that endocannabinoids do. But endocannabinoids are produced by the body whereas cannabinoids are found in cannabis.

The most popular cannabinoids are Delta-9 THC and CBD, in part because they are the most abundant cannabinoids in cannabis. However, there are countless other cannabinoids present in the plant as well.

Some cannabinoids that have been getting a lot of attention lately include CBG, CBN, and Delta-8 THC. Each interacts with the endocannabinoid system in its own way to produce unique benefits.

Quote Icon I can’t believe these Delta-9 Gummies are legal! I was blown away by how strong these gummies are. The combo of THC and CBD is perfect for a really euphoric experience!
Quote Icon

I can’t believe these Delta-9 Gummies are legal! I was blown away by how strong these gummies are. The combo of THC and CBD is perfect for a really euphoric experience!

CBD and the Endocannabinoid System

Unlike other cannabinoids, cannabidiol (CBD) does not interact directly with cannabinoid receptors. Instead, it affects endocannabinoid levels.

Current research asserts that CBD works by preventing enzymes from breaking down endocannabinoids, allowing them to exert a stronger and longer effect than they otherwise would have. Some investigators also suspect that CBD binds with a kind of endocannabinoid receptor that hasn’t yet been discovered.

Research suggests that through its actions in the body, CBD may help with a slew of issues. How you use CBD impacts what issues it’s targeting.

For example, if you use CBD topicals like Crescent Canna’s CBD Freeze Roller or CBD Recovery Cream, CBD will directly target endocannabinoids in the area it’s applied through your skin’s pores, helping reduce issues like pain and inflammation.

If you take CBD Drops, they’ll be more effective for internal issues, or general body issues, like reducing stress by increasing the number of endocannabinoids in your brain.

THC and the Endocannabinoid System

THC is the most famous cannabinoid in cannabis, producing marijuana’s famous psychoactive effects. It interacts with the endocannabinoid system by directly binding to both CB1 and CB2 receptors.

Because it binds with both kinds of receptors, THC exerts a wide range of effects on the body and mind. Research suggests that THC may help stimulate appetite, improve your mood, and reduce queasiness.

Two types of THC currently on the market are Delta-8 THC and Delta-9 THC. Although their physiological and psychological results are similar, Delta-8 THC is only about two-thirds as potent. This makes Delta-8 THC better for people seeking milder psychoactive effects, which our Delta-8 Gummies are perfect for.

The Entourage Effect

According to the theory of the entourage effect, cannabinoids work synergistically. This means that in addition to producing their individual effects, they also enhance the benefits of other cannabinoids in a product.

Crescent Canna’s Delta-9 Gummies contain both Delta-9 THC and CBD. THC produces stimulating and uplifting psychoactive effects; CBD helps you to be calm and relaxed. When you mix them in one product, you get the benefits of both, mutually enhanced.

Crescent Canna’s Full-Spectrum CBD Drops contain cannabigerol (CBG), a cannabinoid with uplifting and energizing effects, and cannabinol (CBN), a cannabinoid with relaxing and soothing effects. Like CBD and THC, these cannabinoids complement each other, mutually enhancing their benefits.

Hemp-Derived Cannabinoid Products

Cannabinoids can have a powerful impact on your body. Try CBD, THC, CBG, and CBN for yourself to experience their benefits.

Crescent Canna’s hemp-derived cannabinoid products are high-quality, high-potency, and lab-tested for purity. Bring balance to your body with cannabinoid products you can trust.

To learn more about our hemp-derived cannabis products and to get incredible deals delivered directly to your inbox, subscribe to the Crescent Canna newsletter. You’ll get a discount code for 30% off just for signing up.

WARNING: Keep THC products out of the reach of children and animals. THC products are for purchase and use only by persons 21 or older. Do not use THC products if you are pregnant or breastfeeding. Consuming THC products may impair your ability to drive and operate machinery and may cause sedation. Use extreme caution. Consult a doctor before using THC products. Do not use them if you are taking medication or may have a health condition.

Helen Lewis

Helen Lewis

Helen Lewis is the Senior Marketing Manager at Crescent Canna. She specializes in writing about cannabis, with a focus on its health benefits. She graduated from Tulane University with a B.A. in English.


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